ITP with severe thrombocytopenia in pregnancy

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منابع مشابه

Fetomaternal outcome in pregnancy with severe thrombocytopenia.

OBJECTIVES STo study the feto-maternal outcome in pregnancy with severe thrombocytopenia. MATERIALS AND METHODS It was an observational study involving 1150 pregnant women with term gestation in labour, who were screened for thrombocytopenia. Ninety-four subjects (8.17%) were found to have thrombocytopenia i.e. platelet count < 1,50,/000/mm3, out of which 47 subjects (group A) had platelet co...

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Therapeutic Options for Immune Thrombocytopenia (ITP) During Pregnancy.

ABSTRACT The incidence of ITP during pregnancy is low. When ITP is suspected it is necessary to perform an extended set of clinical and biological investigations in order to determine the etiology of thrombocytopenia, as the diagnosis of ITP is a process of exclusion, because there is no sensitive and specific diagnostic test so far. The treatment for ITP during pregnancy represents a challenge...

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Long-Term Use of the Thrombopoietin-Mimetic Romiplostim in Children With Severe Chronic Immune Thrombocytopenia (ITP)

BACKGROUND Treatment of chronic severe pediatric ITP is not well studied. In a phase 1/2 12-16-week study, 15/17 romiplostim-treated patients achieved platelet counts ≥50 × 109 /L, and romiplostim treatment was well tolerated. In a subsequent open-label extension (≤109 weeks), 20/22 patients received romiplostim; all achieved platelet counts >50 × 109 /L. Twelve patients continued in a second e...

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Moderate to severe thrombocytopenia during pregnancy.

OBJECTIVE The objective was to investigate obstetric risk factors, complications, and outcomes of pregnancies complicated by moderate to severe thrombocytopenia. MATERIALS AND METHODS A retrospective case-control study comparing 199 pregnant women with moderate to severe thrombocytopenia (platelet count below 100x10(9)/l) with 201 pregnant women without thrombocytopenia, who delivered between...

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Immune thrombocytopenia (ITP): an historical perspective.

See the related ASH 50th Anniversary Review articles under the PLATELETS AND MEGAKARYOCYTOPOIESIS section of the publication ASH 50th Anniversary Reviews: A Salute to the American Society of Hematology. In 1735, two young girls presented to the German physician Paul Gottlieb Werlhof with symptoms of epistaxis and purpura. One young patient had a spontaneous remission, while the second suffered ...

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ژورنال

عنوان ژورنال: Medicine Science | International Medical Journal

سال: 2016

ISSN: 2147-0634

DOI: 10.5455/medscience.2016.05.8411